Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313449 | 0.82 | MEN1 (0.44) | MEN1KMT2ACYP2C9F10ALDH1A1 | |
| SCHEMBL28159610 | 0.79 | KDM4E (0.53) | MEN1KMT2AMAPK1ALDH1A1KDM4E | |
| SCHEMBL27773270 | 0.78 | KDM4E (0.46) | MEN1KMT2ACYP3A4CYP2C9PDGFRA | |
| SCHEMBL27301958 | 0.78 | MEN1 (0.47) | MEN1KMT2ACYP2C9F10ALDH1A1 | |
| SCHEMBL9031893 | 0.75 | ELANE (0.41) | F10ALDH1A1ELANEPRTN3KDM4E | |
| SCHEMBL9029988 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2ACYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL13240831 | 0.69 | AKR1C3 (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2983990 | 0.69 | AKR1C3 (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11335936 | 0.69 | KDM4E (0.49) | KMT2AMAPK1ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL2482531 | 0.68 | AKR1C3 (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107835-A | A process for preparing pharmaceutical composition showing properties in against human immunodeficiency virus | JANSSEN PHARMACEUTICA NV (BE) | 1995-09-06 | — | — | CN | disclosed |
| CN-1058958-A | HIV inhibiting phenylacetamide derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1992-02-26 | — | — | CN | disclosed |