Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029988 | 0.87 | ALDH1A1 (0.43) | ELANEPRTN3ALDH1A1KDM4ECXCL8 | |
| SCHEMBL8830164 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4ECXCL8ADRA1AHPGD | |
| SCHEMBL27313449 | 0.84 | MEN1 (0.44) | ELANEPRTN3ALDH1A1KDM4EADRA1A | |
| SCHEMBL8830236 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CXCL8L3MBTL1HPGDRAB9A | |
| SCHEMBL9031270 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1KDM4ECXCL8HPGDRAB9A | |
| SCHEMBL27351007 | 0.75 | MEN1 (0.39) | ELANEPRTN3ALDH1A1KDM4EHPGD | |
| SCHEMBL14440013 | 0.74 | CXCL8 (0.43) | ALDH1A1KDM4ECXCL8LMNACYP1A2 | |
| SCHEMBL5967627 | 0.73 | PTGS2 (0.44) | ALDH1A1KDM4ECXCL8ADRA1ALMNA | |
| Loviride SCHEMBL247782 | 0.72 | ALOX15 (0.39) | ALDH1A1KDM4EL3MBTL1HPGDRAB9A | |
| Loviride SCHEMBL29457001 | 0.72 | ALOX15 (0.39) | ALDH1A1KDM4EL3MBTL1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538301-B1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1996-10-30 | — | — | EP | disclosed |
| US-5556886-A | VIRICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-09-17 | — | — | US | disclosed |