SCHEMBL27353074

SCHEMBL27353074

C=C(C)C(OC(=O)Nc1ccc(Br)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
FPR1 P21462 1/20 0.43
LDHA P00338 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 2/20 0.42
EPHX1 P07099 1/20 0.42
F13A1 P00488 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836146 0.87 GAA (0.44) NPC1RAB9ASMN1; SMN2TSHRNFKB1
SCHEMBL9836062 0.86 NAPRT (0.47) NPC1RAB9ASMN1; SMN2TSHRALDH1A1
SCHEMBL27309652 0.85 MEN1 (0.43) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL27344660 0.85 FPR2 (0.45) FPR2NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL27311663 0.79 HTT (0.48) FPR2NPC1RAB9AALDH1A1MAPT
SCHEMBL27313983 0.75 KDM4E (0.49) NPC1RAB9ATSHRALDH1A1MAPT
SCHEMBL9833817 0.75 HPGD (0.44) FPR2NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL9833996 0.75 SMN1; SMN2 (0.45) NPC1RAB9ASMN1; SMN2TSHRALDH1A1
SCHEMBL9835863 0.74 SMN1; SMN2 (0.44) NPC1RAB9ASMN1; SMN2TSHRNFKB1
SCHEMBL9836837 0.73 TDP1 (0.46) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed