SCHEMBL27309652

SCHEMBL27309652

C=C(C)C(OC(=O)Nc1ccc(F)cc1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 2/20 0.43
CASP3 P42574 1/20 0.43
MAPT P10636 3/20 0.43
KLK7 P49862 1/20 0.42
ALDH1A1 P00352 2/20 0.42
TGM2 P21980 1/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
FAAH O00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835566 0.87 ALDH1A1 (0.44) MEN1KMT2APOLBCASP3MAPT
SCHEMBL9836062 0.86 NAPRT (0.47) MEN1KMT2APOLBCASP3MAPT
SCHEMBL27353074 0.85 FPR2 (0.44) MEN1KMT2AMAPTALDH1A1TGM2
SCHEMBL27353072 0.85 FAAH (0.44) MEN1KMT2APOLBCASP3MAPT
SCHEMBL27313983 0.83 KDM4E (0.49) MEN1KMT2ACASP3MAPTALDH1A1
SCHEMBL9834356 0.81 HTT (0.47) POLBMAPTALDH1A1NPC1RAB9A
SCHEMBL27311663 0.79 HTT (0.48) MEN1KMT2AMAPTALDH1A1NPC1
SCHEMBL17904708 0.76 NPC1 (0.67) MEN1KMT2ACASP3MAPTKLK7
SCHEMBL9836991 0.75 MAPT (0.46) MEN1KMT2ACASP3MAPTKLK7
SCHEMBL9833996 0.75 SMN1; SMN2 (0.45) MEN1KMT2AMAPTKLK7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed