Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27353257 | 0.76 | AKT1 (0.59) | HTR1AHTR2CAKT1CDK2 | |
| SCHEMBL8948338 | 0.76 | HTR1A (0.54) | HTR1ASIGMAR1HTR2C | |
| Hydrochloric Acid SCHEMBL8871795 | 0.72 | SIGMAR1 (0.57) | HTR1ASIGMAR1HTR2C | |
| SCHEMBL9685737 | 0.71 | SIGMAR1 (0.64) | HTR1ASIGMAR1HTR2C | |
| SCHEMBL7761420 | 0.70 | SIGMAR1 (0.59) | HTR1ASIGMAR1HTR2C | |
| SCHEMBL8114163 | 0.70 | SIGMAR1 (0.61) | HTR1ASIGMAR1HTR2C | |
| SCHEMBL4614132 | 0.69 | EPHX1 (0.50) | HTR2CAKT1CDK2 | |
| Hydrochloric Acid SCHEMBL8870817 | 0.69 | SIGMAR1 (0.60) | HTR1ASIGMAR1HTR2C | |
| SCHEMBL9684012 | 0.68 | MAPT (0.61) | HTR1ASIGMAR1HTR2C | |
| SCHEMBL9484568 | 0.68 | SIGMAR1 (0.62) | HTR1ASIGMAR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050601-C | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-03-22 | — | — | CN | disclosed |
| CN-1111626-A | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-15 | — | — | CN | disclosed |