Isopropylbenzene

Isopropylbenzene

SCHEMBL27354567

CC(C)c1ccccc1.CCCCCCCCCCCCBr

nearest known ligand 0.45

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.44
KCNH2 Q12809 3/20 0.43
ASAH1 Q13510 2/20 0.42
ALDH1A1 P00352 1/20 0.42
ACER2 Q5QJU3 1/20 0.42
NAAA Q02083 3/20 0.41
EPHX1 P07099 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
CYP19A1 P11511 3/20 0.39
TAAR1 Q96RJ0 1/20 0.38
POLB P06746 1/20 0.38
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylbenzene SCHEMBL2596977 0.90 HTR2A (0.50) HTR2AKCNH2ASAH1ALDH1A1ACER2
Isopropylbenzene SCHEMBL18343980 0.90 HTR2A (0.50) HTR2AKCNH2ASAH1ALDH1A1ACER2
Hexadecane SCHEMBL28192744 0.90 HTR2A (0.50) HTR2AKCNH2ASAH1ALDH1A1ACER2
Isopropylbenzene SCHEMBL8837125 0.88 HTR2A (0.47) HTR2AKCNH2ASAH1ALDH1A1ACER2
SCHEMBL27991050 0.85 HTR2A (0.45) HTR2AKCNH2ASAH1ALDH1A1ACER2
Dodecanol SCHEMBL27992743 0.81 LMNA (0.50) HTR2AASAH1ALDH1A1ACER2NAAA
Isopropylbenzene SCHEMBL28826494 0.81 HTR2A (0.44) HTR2AKCNH2ASAH1ALDH1A1ACER2
Dodecylamine SCHEMBL1859156 0.81 HTR2A (0.51) HTR2AALDH1A1EPHX1TAAR1
Chlorobenzene SCHEMBL27613825 0.80 TSHR (0.46) KCNH2ALDH1A1NAAAEPHX1CES2
Isopropylbenzene SCHEMBL8668126 0.79 SIGMAR1 (0.58) ASAH1ALDH1A1ACER2NAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1051552-A ACAT INHIBITORS WARNER LAMBERT CO (US) 1991-05-22 CN disclosed