SCHEMBL273550

SCHEMBL273550

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](Cl)(Cl)(C1C(C(C)C)=Cc2c(-c3cccc4ccccc34)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2513908 0.94 NPC1 (0.34) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL5584026 0.94
SCHEMBL5890104 0.93 NPC1 (0.33) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL1024768 0.92
SCHEMBL137885 0.92 ENPP3 (0.32) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL1026090 0.91
SCHEMBL27854154 0.91 NPC1 (0.32) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL1023601 0.90
SCHEMBL1022253 0.90
SCHEMBL273299 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618912-B2 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
US-20060166813-A1 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2006-07-27 US claimed
EP-2576642-B1 PROCESS FOR PREPARING A SUPPORTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, THE CATALYST SYSTEM AND ITS USE BASELL POLYOLEFINE GMBH (DE) 2017-08-16 EP disclosed
EP-2513166-B1 PROCESS FOR THE PREPARATION OF SUPPORTED CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2017-04-05 EP disclosed
EP-1824888-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2017-01-18 EP disclosed
US-8999875-B2 Process for preparing a supported catalyst system for olefin polymerization, the catalyst system and its use BASELL POLYOLEFINE GMBH (DE) 2015-04-07 US disclosed
EP-1740626-B1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE BASELL POLYOLEFINE GMBH (DE) 2014-10-22 EP disclosed
US-8859451-B2 Process for the preparation of supported catalysts BASELL POLYOLEFINE GMBH (DE) 2014-10-14 US disclosed
US-8680001-B2 Preparation of supported catalyst systems containing reduced amounts of aluminoxanes BASELL POLYOLEFINE GMBH (DE) 2014-03-25 US disclosed
US-20130072652-A1 Process for preparing a supported catalyst system for olefin polymerization, the catalyst system and its use BASELL POLYOLEFINE GMBH (DE) 2013-03-21 US disclosed
US-8399536-B2 Irradiated polyolefin composition comprising a non-phenolic stabilizer Basell Poliolefine Italia, s.r.l. (IT) 2013-03-19 US disclosed
WO-2004056482-A1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-07-08 WO disclosed
WO-2004041871-A1 PREPARATION OF CATALYST COMPOSITIONS HAVING IMPROVED ACTIVITY BASELL POLYOLEFINE GMBH (DE) 2004-05-21 WO disclosed
WO-2004020479-A2 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-03-11 WO disclosed
WO-2004018489-A1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-03-04 WO disclosed
EP-1392710-A1 REDUCTION OF THE CONCENTRATION OF INORGANIC BY-PRODUCTS AND ORGANOMETALLIC BY-PRODUCTS IN THE PREPARATION OF METALLOCENES AND ECONOMICAL RECOVERY OF THE STARTING MATERIALS USED Basell Polyolefine GmbH (DE) 2004-03-03 EP disclosed
US-20040033890-A1 Catalyst system for carrying out olefin polymerization comprising a calcined hydro-talcite serving as a supporting material LYONDELL CHEMICAL TECHNOLOGY, L.P. 2004-02-19 US disclosed
WO-2004007569-A1 PREPARATION OF CATALYST SYSTEMS BASELL POLYOLEFINE GMBH (DE) 2004-01-22 WO disclosed
US-20030176275-A1 Catalytic solid supported on calcined hydrotalcite for olefinic polymerisation BASELL POLYOLEFINE GMBH (DE) 2003-09-18 US disclosed
WO-2002096920-A1 REDUCTION OF THE CONCENTRATION OF INORGANIC BY-PRODUCTS AND ORGANOMETALLIC BY-PRODUCTS IN THE PREPARATION OF METALLOCENES AND ECONOMICAL RECOVERY OF THE STARTING MATERIALS USED BASELL POLYOLEFINE GMBH (DE) 2002-12-05 WO disclosed