Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513908 | 0.99 | NPC1 (0.34) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL273550 | 0.93 | NPC1 (0.31) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28806583 | 0.90 | ALDH1A1 (0.31) | — | |
| SCHEMBL5890634 | 0.89 | NPC1 (0.31) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5584026 | 0.87 | — | — | |
| SCHEMBL1026090 | 0.87 | — | — | |
| SCHEMBL1022253 | 0.86 | — | — | |
| SCHEMBL1023601 | 0.86 | — | — | |
| SCHEMBL1024768 | 0.86 | — | — | |
| SCHEMBL5890345 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122498-B2 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-10-17 | — | — | US | disclosed |