SCHEMBL2735503

SCHEMBL2735503

O=P(c1cccc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)n1)(c1cccc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)n1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
RXFP1 Q9HBX9 1/20 0.31
PDE10A Q9Y233 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
LDHA P00338 1/20 0.30
ASIC3 Q9UHC3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12150886 0.91 KDM4E (0.38) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL12150722 0.84 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL2735424 0.82 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL12150795 0.82 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL15867543 0.81 L3MBTL1 (0.53) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL29446477 0.81 L3MBTL1 (0.52) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL29353726 0.81 L3MBTL1 (0.52) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL8400384 0.81 L3MBTL1 (0.52) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL12150931 0.81 FBP1 (0.34) KDM4EATML3MBTL1
SCHEMBL12150888 0.81 KDM4E (0.38) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
EP-2403029-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-01-04 EP disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed