Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362354 | 0.89 | PDE5A (0.51) | PDE5A | |
| SCHEMBL27447268 | 0.89 | PDE5A (0.50) | PDE5A | |
| SCHEMBL27620033 | 0.89 | PDE5A (0.50) | PDE5A | |
| SCHEMBL27447274 | 0.88 | DHFR (0.49) | PDE5A | |
| SCHEMBL27357114 | 0.88 | PDE5A (0.53) | PDE5AMPO | |
| SCHEMBL27383523 | 0.87 | PDE5A (0.40) | PDE5AADORA2A | |
| SCHEMBL27364614 | 0.86 | PDE5A (0.38) | PDE5AADORA2A | |
| SCHEMBL27355412 | 0.84 | SMN1; SMN2 (0.43) | PDE5A | |
| SCHEMBL27377308 | 0.83 | TUBB4A (0.44) | PDE5A | |
| SCHEMBL27363427 | 0.83 | PDE10A (0.42) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071164-A | Nitrogen-containing heterocycle compound | EISAI CO LTD (JP) | 1993-04-21 | — | — | CN | disclosed |