Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18843966 | 0.93 | NAAA (0.42) | KMT2AALDH1A1POLBHPGDNAAA | |
| SCHEMBL9747768 | 0.77 | — | — | |
| SCHEMBL27355976 | 0.77 | KMT2A (0.44) | KMT2AALDH1A1PKMTRPA1POLB | |
| SCHEMBL9747766 | 0.77 | — | — | |
| SCHEMBL9747757 | 0.77 | — | — | |
| SCHEMBL12073789 | 0.76 | ALDH1A1 (0.43) | KMT2AALDH1A1PKMPOLBHTT | |
| SCHEMBL19560711 | 0.76 | MEN1 (0.37) | KMT2AALDH1A1PKMCYP2C9NPSR1 | |
| SCHEMBL19560656 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL25780330 | 0.72 | MALT1 (0.34) | KMT2AALDH1A1PKMNPSR1 | |
| SCHEMBL5509671 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |