SCHEMBL27356099

SCHEMBL27356099

CC1CC2CC(NCC(=O)N3Cc4ccccc4C3)(C1)CC(C)(OC(=O)NC(CCCCNC(=O)OCc1ccccc1)C(=O)O)C2

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 17/20 0.53
▸ DPP9 Q86TI2 17/20 0.53
▸ GLMN Q92990 2/20 0.46
▸ DPP7 Q9UHL4 1/20 0.45
▸ TGM2 P21980 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27356105 0.88 DPP8 (0.69) DPP8DPP9GLMN
SCHEMBL30685134 0.88 DPP8 (0.69) DPP8DPP9GLMN
SCHEMBL27357732 0.81 DPP8 (0.55) DPP8DPP9GLMNDPP7TGM2
SCHEMBL27356085 0.80 DPP9 (0.73) DPP8DPP9GLMN
SCHEMBL30685198 0.77 DPP8 (0.59) DPP8DPP9GLMN
SCHEMBL27356370 0.77 DPP8 (0.59) DPP8DPP9GLMN
SCHEMBL27356568 0.77 SIRT2 (0.48) DPP8DPP9DPP7TGM2
SCHEMBL27356064 0.76 DPP9 (0.74) DPP8DPP9GLMN
SCHEMBL27356038 0.76 DPP9 (0.73) DPP8DPP9GLMN
SCHEMBL27356025 0.75 DPP9 (0.67) DPP8DPP9GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
Send feedback