SCHEMBL27356370

SCHEMBL27356370

NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 20/20 0.59
▸ DPP9 Q86TI2 20/20 0.59
▸ GLMN Q92990 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685198 1.00 DPP8 (0.59) DPP8DPP9GLMN
SCHEMBL27356105 0.88 DPP8 (0.69) DPP8DPP9GLMN
SCHEMBL30685134 0.88 DPP8 (0.69) DPP8DPP9GLMN
SCHEMBL27356571 0.79 SIRT2 (0.50) DPP8
SCHEMBL27357732 0.79 DPP8 (0.55) DPP8DPP9GLMN
SCHEMBL30685099 0.78 DPP8 (0.67) DPP8DPP9GLMN
SCHEMBL27356463 0.78 DPP8 (0.67) DPP8DPP9GLMN
SCHEMBL30685149 0.77 DPP8 (0.63) DPP8DPP9GLMN
SCHEMBL27356099 0.77 DPP8 (0.53) DPP8DPP9GLMN
SCHEMBL30685031 0.77 DPP8 (0.61) DPP8DPP9GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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