SCHEMBL27356751

SCHEMBL27356751

CC(CNC(=O)Oc1ccccc1)CNC(=O)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
ALDH1A1 P00352 3/20 0.50
GAA P10253 2/20 0.50
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TAAR1 Q96RJ0 2/20 0.49
PRMT5 O14744 2/20 0.48
WDR77 Q9BQA1 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
MAPT P10636 1/20 0.47
KCNA5 P22460 1/20 0.46
CYP1A2 P05177 1/20 0.46
SLC1A3 P43003 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10664573 0.89 NPC1 (0.57) NPC1RAB9AALDH1A1GAAMTNR1A
SCHEMBL23766625 0.88 NPC1 (0.56) NPC1RAB9AALDH1A1GAAMTNR1A
SCHEMBL27234548 0.85 RAB9A (0.54) NPC1RAB9AALDH1A1GAAMTNR1A
SCHEMBL23766641 0.84 PRMT5 (0.59) NPC1RAB9AALDH1A1GAAMTNR1A
SCHEMBL2396325 0.83 NPC1 (0.51) NPC1RAB9AALDH1A1GAAMTNR1A
SCHEMBL9623296 0.83 RAB9A (0.51) NPC1RAB9AALDH1A1GAAMEN1
SCHEMBL28897234 0.82 RAB9A (0.50) NPC1RAB9AALDH1A1GAAMEN1
SCHEMBL14461336 0.81 NPC1 (0.50) NPC1RAB9AALDH1A1GAAMTNR1A
SCHEMBL126140 0.79 HSD17B10 (0.54) NPC1RAB9AALDH1A1GAAMEN1
SCHEMBL12370956 0.79 NPC1 (0.55) NPC1RAB9AALDH1A1GAAMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US disclosed