SCHEMBL23766641

SCHEMBL23766641

O=C(NCC(O)CNC(=O)Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 2/20 0.59
WDR77 Q9BQA1 1/20 0.59
HSD17B10 Q99714 1/20 0.51
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
TAAR1 Q96RJ0 2/20 0.46
GAA P10253 2/20 0.46
SLC1A3 P43003 1/20 0.46
ALDH1A1 P00352 5/20 0.46
MAPT P10636 2/20 0.45
FAAH O00519 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
KMT2A Q03164 1/20 0.44
MTNR1A P48039 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23766625 0.86 NPC1 (0.56) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL10664573 0.84 NPC1 (0.57) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL27356751 0.84 NPC1 (0.57) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL28897234 0.84 RAB9A (0.50) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL14461336 0.83 NPC1 (0.50) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL9623296 0.81 RAB9A (0.51) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL2396325 0.81 NPC1 (0.51) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL7344923 0.80 PRMT5 (0.46) PRMT5WDR77HSD17B10RAB9ANPC1
SCHEMBL13055389 0.80 TAAR1 (0.60) HSD17B10RAB9ANPC1TAAR1GAA
SCHEMBL9778357 0.80 HSD17B10 (0.57) HSD17B10RAB9ANPC1TAAR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827586-B2 Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-11-28 US disclosed
US-11827586-B2 Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-11-28 US disclosed
US-20210253517-A1 METHOD FOR PRODUCING AMINO ACID AMINOALKYL ESTER OR INORGANIC ACID SALT THEREOF ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253517-A1 METHOD FOR PRODUCING AMINO ACID AMINOALKYL ESTER OR INORGANIC ACID SALT THEREOF SLC6A15, SLC6A19, ALAD PRMT5 741/4885WDR77 2296/4885HSD17B10 1038/4885
US-11827586-B2 Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof SLC6A15, SLC6A19, ALAD PRMT5 741/4885WDR77 2296/4885HSD17B10 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.