SCHEMBL27357686

SCHEMBL27357686

O=C(NC(c1ccc(F)cc1)c1ccc(F)cc1)OC12CC3CC4CC(NCC(=O)N5Cc6ccccc6C5)(C1)C34C2

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 20/20 0.68
▸ DPP9 Q86TI2 20/20 0.68
▸ GLMN Q92990 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685090 0.81 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27356073 0.81 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27356064 0.74 DPP9 (0.74) DPP8DPP9GLMN
SCHEMBL27356093 0.73 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30685126 0.73 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27357688 0.69 DPP9 (0.76) DPP8DPP9GLMN
SCHEMBL27357812 0.67 DPP9 (0.62) DPP8DPP9GLMN
SCHEMBL27356085 0.66 DPP9 (0.73) DPP8DPP9GLMN
SCHEMBL27356226 0.65 DPP9 (0.68) DPP8DPP9GLMN
SCHEMBL27357603 0.64 DPP9 (0.59) DPP8DPP9GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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