⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829487 | 0.85 | — | — | |
| SCHEMBL27377127 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL11572911 | 0.81 | AKR1B1 (0.33) | — | |
| SCHEMBL30468514 | 0.79 | CA2 (0.33) | — | |
| SCHEMBL27523647 | 0.73 | — | — | |
| SCHEMBL3851809 | 0.73 | — | — | |
| SCHEMBL3851806 | 0.73 | — | — | |
| SCHEMBL31413916 | 0.72 | — | — | |
| SCHEMBL30663904 | 0.72 | HTT (0.31) | — | |
| SCHEMBL27594924 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073103-C | Compounds and compositions for treating diseases associated with tryptase activity | ARRIS PHARM CORP (US) | 2001-10-17 | — | — | CN | claimed |
| CN-1226892-A | Novel compounds and compositions for the treatment of diseases associated with tryptase activity | ARRIS PHARM CORP (US) | 1999-08-25 | — | — | CN | claimed |
| CN-1073103-C | Compounds and compositions for treating diseases associated with tryptase activity | ARRIS PHARM CORP (US) | 2001-10-17 | — | — | CN | disclosed |
| CN-1226892-A | Novel compounds and compositions for the treatment of diseases associated with tryptase activity | ARRIS PHARM CORP (US) | 1999-08-25 | — | — | CN | disclosed |