⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24349596 | 1.00 | — | — | |
| SCHEMBL10048334 | 0.79 | — | — | |
| SCHEMBL7791038 | 0.79 | SLC6A4 (0.31) | — | |
| SCHEMBL22705602 | 0.76 | — | — | |
| SCHEMBL2989879 | 0.76 | — | — | |
| SCHEMBL15467024 | 0.76 | — | — | |
| SCHEMBL25591225 | 0.75 | PIK3CD (0.35) | — | |
| SCHEMBL384098 | 0.75 | — | — | |
| SCHEMBL17921493 | 0.74 | PRMT3 (0.36) | — | |
| SCHEMBL9541597 | 0.74 | PRMT3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297148-B1 | NOVEL DERIVATIVES OF (BRIDGED PIPERAZINYL)-1-ALCANONE AND USE THEREOF AS P75 INHIBITORS | SANOFI SA (FR) | 2012-01-04 | — | — | EP | disclosed |