Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 5/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27358351 | 1.00 | ELANE (0.43) | ELANECTRB1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27363486 | 0.88 | ELANE (0.32) | ELANECTRB1 | |
| SCHEMBL27377429 | 0.83 | ELANE (0.35) | ELANECTRB1 | |
| SCHEMBL27379949 | 0.75 | TAAR1 (0.37) | — | |
| SCHEMBL27551816 | 0.72 | ELANE (0.45) | ELANECTRB1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30122568 | 0.67 | KDM4E (0.34) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27362385 | 0.65 | TAAR1 (0.37) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL6497235 | 0.60 | ELANE (1.00) | ELANECTRB1 | |
| SCHEMBL28667663 | 0.59 | GAA (0.61) | SMN1; SMN2KDM4EALDH1A1HPGDEGFR | |
| SCHEMBL15137210 | 0.56 | ALDH1A1 (0.62) | SMN1; SMN2KDM4EALDH1A1EGFRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070480-C | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 2001-09-05 | — | — | CN | disclosed |