SCHEMBL27363486

SCHEMBL27363486

Cc1cccc2c1COC(N[C@H](C)c1ccc(I)cc1)=N2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.32
CTRB1 P17538 3/20 0.32
ACACB O00763 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27358349 0.88 ELANE (0.43) ELANECTRB1
SCHEMBL27358351 0.88 ELANE (0.43) ELANECTRB1
SCHEMBL27377429 0.83 ELANE (0.35) ELANECTRB1
SCHEMBL27363485 0.75 GAA (0.32)
SCHEMBL7441267 0.68 CFB (0.36)
SCHEMBL30122568 0.67 KDM4E (0.34)
SCHEMBL27362385 0.65 TAAR1 (0.37)
SCHEMBL27379949 0.63 TAAR1 (0.37)
SCHEMBL6506330 0.60 ELANE (0.80) ELANECTRB1
SCHEMBL8285882 0.56 ALDH1A1 (0.50) ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1070480-C 2-amino-benzoxanones for the treatment of viral infections SEARLE & CO (US) 2001-09-05 CN disclosed