Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL27638588 | 0.91 | FFAR4 (0.59) | FFAR4FFAR1TSHRGPR84AKR1B1 | |
| Heptanoate SCHEMBL27881470 | 0.86 | FFAR4 (0.53) | FFAR4FFAR1TSHRGPR84AKR1B1 | |
| Thioglycolic Acid SCHEMBL27469079 | 0.82 | LMNA (0.37) | LMNATSHRALDH1A1SLC22A6PDE4A | |
| Glycerin SCHEMBL3683065 | 0.81 | FFAR4 (0.46) | FFAR4FFAR1LMNATSHRNFKB1 | |
| Glycerin SCHEMBL28714217 | 0.81 | FFAR4 (0.46) | FFAR4FFAR1LMNATSHRNFKB1 | |
| Glycerin SCHEMBL28492784 | 0.81 | FFAR4 (0.46) | FFAR4FFAR1LMNATSHRNFKB1 | |
| Adipic Acid SCHEMBL28688445 | 0.80 | LMNA (0.61) | FFAR4FFAR1LMNATSHRNFKB1 | |
| Adipic Acid SCHEMBL270756 | 0.80 | LMNA (0.61) | FFAR4FFAR1LMNATSHRNFKB1 | |
| SCHEMBL11890983 | 0.80 | — | — | |
| SCHEMBL11890981 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060491-C | Thermoplastic polycarbonate resin composition | QIMEI IND CO LTD (CN) | 2001-01-10 | — | — | CN | disclosed |
| CN-1172132-A | Thermoplastic polycarbonate resin composition | QIMEI IND CO LTD (CN) | 1998-02-04 | — | — | CN | disclosed |