Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28688445 | 1.00 | LMNA (0.61) | LMNATSHRNFKB1PMP22GPR84 | |
| Glycerin SCHEMBL28489790 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL30008072 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL270082 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL1495263 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL31652315 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL31615119 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Glycerin SCHEMBL29687651 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Pimelic Acid SCHEMBL29894654 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 | |
| Glycerin SCHEMBL3607211 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590350-A1 | COATED SUBSTRATE AND METHOD FOR FORMING COATED SUBSTRATE | The Secant Group, LLC (US) | 2025-07-30 | — | — | EP | claimed |
| WO-2025111503-A1 | A PRESSURE-SENSITIVE BIOADHESIVE FOR WET TISSUES AND ORGANS | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| WO-2024256602-A1 | METHOD FOR STIMULATING LATEX PRODUCTION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-12-19 | — | — | WO | claimed |
| EP-4454670-A1 | POLYMER-CERAMIC BIOCOMPOSITES WITH PRO-REGENERATIVE PROPERTIES FOR FILING BONE DEFECTS AND REGENERATING BONE TISSUE AND METHOD OF OBTAINING THEM | Siec Badawcza Lukasiewicz - Instytut Ceramiki i Materialow Budowlanych (PL) | 2024-10-30 | — | — | EP | claimed |
| WO-2024064718-A1 | COATED SUBSTRATE AND METHOD FOR FORMING COATED SUBSTRATE | THE SECANT GROUP, LLC (US) | 2024-03-28 | — | — | WO | claimed |
| US-20240100222-A1 | COATED SUBSTRATE AND METHOD FOR FORMING COATED SUBSTRATE | JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT | 2024-03-28 | — | — | US | claimed |
| CN-117467272-A | Ultralow temperature resistant rubber plastic product and preparation method thereof | 苏州万润绝缘材料有限公司 | 2024-01-30 | — | — | CN | claimed |
| US-20230192944-A1 | METHOD OF PREPARING A DEGRADABLE PRODUCT | UNIV NAT TSING HUA (TW) | 2023-06-22 | — | — | US | claimed |
| CN-115944564-A | Traditional Chinese medicine contained lipstick for reducing internal heat and preparation process thereof | 浙江百姿化妆品股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| US-11459848-B2 | Degradable aliphatic polyester fluid | LYONDELLBASELL ADVANCED POLYMERS INC. (US) | 2022-10-04 | — | — | US | claimed |
| CN-113278273-A | Degradable microparticle, degradable product containing same and application | 王洁 | 2021-08-20 | — | — | CN | claimed |
| CN-107556645-B | Elastomer insulation coating material for charging pile cable and preparation method thereof | 东莞海铂新材料科技有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-105237922-A | High performance fluorine rubber protective sleeve cable | ANHUI LAND GROUP CO LTD | 2016-01-13 | — | — | CN | claimed |
| US-20080260900-A1 | Degradable Polymer for Chewing Gum | GUMLINK A/S | 2008-10-23 | — | — | US | claimed |
| EP-1828279-A1 | DEGRADABLE POLYMER FOR CHEWING GUM | Gumlink A/S (DK) | 2007-09-05 | — | — | EP | claimed |
| WO-2006066573-A1 | DEGRADABLE POLYMER FOR CHEWING GUM | GUMLINK A/S (DK) | 2006-06-29 | — | — | WO | claimed |
| US-20260096990-A1 | POLYMERIC DELIVERY SYSTEMS | SECANT GROUP LLC (US) | 2026-04-09 | — | — | US | disclosed |
| US-12590333-B1 | N-Myc-interactor protein as a marker for chronic lung disease and uses thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2026-03-31 | — | — | US | disclosed |
| US-3959201-A | High solids, water thinnable compositions | PPG INDUSTRIES, INC. (US) | 1976-05-25 | — | — | US | disclosed |
| US-3945831-A | Photosensitive resins containing a thienylacrylic acid ester or amide group | FUJI PHOTO FILM CO., LTD. (JA) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260096990-A1 | POLYMERIC DELIVERY SYSTEMS | NFATC1, CHMP4B, PARG | LMNA 979/4885TSHR 1875/4885NFKB1 400/4885 |
| US-12590333-B1 | N-Myc-interactor protein as a marker for chronic lung disease and uses thereof | MYCBP, MYC, MYCBP2 | LMNA 3692/4885TSHR 3879/4885NFKB1 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.