Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522223 | 0.80 | MAOB (0.53) | MAOBTDP1L3MBTL1KMT2AMAPT | |
| SCHEMBL13854257 | 0.73 | MAOB (0.59) | MAOBTDP1L3MBTL1KMT2AMAPT | |
| SCHEMBL7771818 | 0.73 | ALDH1A1 (0.31) | MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5253085 | 0.72 | MAPT (0.50) | MAOBTDP1L3MBTL1MAPTMAPK1 | |
| SCHEMBL688159 | 0.71 | CYP3A4 (0.46) | KMT2AMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29198809 | 0.70 | MAOB (0.59) | MAOBTDP1L3MBTL1KMT2AMAPT | |
| SCHEMBL10523332 | 0.70 | MAOB (0.44) | MAOBTDP1L3MBTL1KMT2AMAPT | |
| SCHEMBL9789581 | 0.70 | MAOB (0.59) | MAOBTDP1L3MBTL1KMT2AMAPT | |
| SCHEMBL7775193 | 0.70 | MAOB (0.59) | MAOBTDP1L3MBTL1KMT2AMAPT | |
| SCHEMBL8480468 | 0.69 | MAPT (0.61) | MAOBTDP1L3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073161-A | ET (ENDOTHELIN) receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-06-16 | — | — | CN | disclosed |