Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 17/20 | 0.43 |
| ▸ | ELOC | Q15369 | 6/20 | 0.39 |
| ▸ | ELOB | Q15370 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360158 | 0.91 | VHL (0.42) | VHLELOCELOBMAPK1DPP4 | |
| SCHEMBL30760178 | 0.91 | VHL (0.42) | VHLELOCELOBMAPK1DPP4 | |
| SCHEMBL27359569 | 0.88 | VHL (0.44) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL30760164 | 0.86 | CYP3A4 (0.43) | VHLELOCELOBMAPK1 | |
| SCHEMBL30760153 | 0.86 | VHL (0.40) | VHLELOCELOB | |
| SCHEMBL30760065 | 0.85 | VHL (0.41) | VHLELOCELOB | |
| SCHEMBL24757103 | 0.85 | VHL (0.44) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL30760038 | 0.82 | VHL (0.51) | VHLELOCELOBMAPK1DPP4 | |
| SCHEMBL26648479 | 0.82 | VHL (0.44) | VHLELOCELOBDPP4DPP8 | |
| SCHEMBL26648474 | 0.82 | VHL (0.44) | VHLELOCELOBDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |