Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27359621 | 0.81 | PDE10A (0.37) | PDE10AALDH1A1PARP1LMNAPSMB8 | |
| SCHEMBL27359788 | 0.80 | PDE10A (0.38) | PDE10ALMNAPSMB8GRM5SLC9A1 | |
| SCHEMBL27359779 | 0.80 | PSMB8 (0.46) | ALDH1A1PARP1MAOBLMNAPSMB8 | |
| SCHEMBL27359777 | 0.73 | PDE10A (0.38) | PDE10ALRRK2ALDH1A1PARP1LMNA | |
| SCHEMBL9389564 | 0.72 | KDM4E (0.42) | ALDH1A1MEN1KMT2ASLC9A1KEAP1 | |
| SCHEMBL28226985 | 0.71 | PARP1 (0.35) | PDE10AALDH1A1PARP1MAOBHSP90AB1 | |
| SCHEMBL13106207 | 0.71 | HSP90AB1 (0.39) | PDE10AALDH1A1PARP1MAOBHSP90AB1 | |
| SCHEMBL16252841 | 0.70 | ALDH1A1 (0.43) | PDE10ALRRK2ALDH1A1DYRK1ALMNA | |
| SCHEMBL27359783 | 0.70 | PTPN11 (0.39) | LMNAPSMB8GRM5 | |
| SCHEMBL28192985 | 0.69 | ALDH1A1 (0.34) | ALDH1A1PARP1MAOBHSP90AB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026536-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | GRIFFITH UNIVERSITY (AU) | 2024-02-08 | — | — | WO | disclosed |