Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106353 | 0.72 | HTR2C (0.36) | PARP1KAT2BMEN1KMT2APDE10A | |
| SCHEMBL28226985 | 0.72 | PARP1 (0.35) | HSP90AB1PARP1KAT2BMAOBMEN1 | |
| SCHEMBL27359770 | 0.71 | PDE10A (0.38) | HSP90AB1PARP1KAT2BMAOBMEN1 | |
| SCHEMBL13106202 | 0.71 | MPO (0.42) | MEN1KMT2AALDH1A1SLC9A1KEAP1 | |
| SCHEMBL28192985 | 0.70 | ALDH1A1 (0.34) | HSP90AB1PARP1KAT2BMAOBMEN1 | |
| SCHEMBL13106209 | 0.69 | ALDH1A1 (0.44) | HSP90AB1KAT2BMEN1KMT2AALDH1A1 | |
| SCHEMBL8536634 | 0.69 | PARP1 (0.36) | HSP90AB1PARP1KAT2BMAOBMEN1 | |
| SCHEMBL13106212 | 0.66 | HTT (0.38) | HSP90AB1PARP1MEN1KMT2APDE10A | |
| SCHEMBL13106216 | 0.66 | KDM4E (0.33) | HSP90AB1MEN1KMT2APDE10ABCHE | |
| SCHEMBL25235188 | 0.65 | NQO2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812045-B2 | Antifungal triazole derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-10-12 | — | — | US | disclosed |
| US-20080194661-A1 | Antifungal Triazole Derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194661-A1 | Antifungal Triazole Derivatives | ERG28, CYP51A1, CYP3A43 | HSP90AB1 975/4885PARP1 2201/4885KAT2B 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.