SCHEMBL2736001

SCHEMBL2736001

COCNc1nc(C)nc(N(COC)C(C)O)n1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP7 P55210 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14885777 0.79
SCHEMBL14817365 0.79 KMT2A (0.36) ALDH1A1TSHRMAPK1SMN1; SMN2GAA
SCHEMBL14885769 0.78
SCHEMBL14817371 0.78 CRHR1 (0.33) ALDH1A1TSHRMAPK1CASP7SMN1; SMN2
SCHEMBL14817372 0.78 GAA (0.33) GAA
SCHEMBL13324807 0.73 PIK3CA (0.34) GAA
SCHEMBL12799915 0.73 GAA (0.43) GAA
SCHEMBL5954721 0.73 GAA (0.43) GAA
SCHEMBL14472261 0.71
SCHEMBL17880267 0.70 ALDH1A1 (0.35) ALDH1A1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8679709-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and film forming coating solution FUJI XEROX CO., LTD. (JP) 2014-03-25 US disclosed
US-8535861-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2013-09-17 US disclosed
US-8090298-B2 Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-01-03 US disclosed
US-20100247148-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-09-30 US disclosed
US-20100104316-A1 ELECTROSTATIC CHARGING MEMBER, ELECTROSTATIC CHARGING DEVICE, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-04-29 US disclosed
US-20090238602-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-09-24 US disclosed
US-20090004583-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND FILM FORMING COATING SOLUTION FUJI XEROX CO., LTD. (JP) 2009-01-01 US disclosed