Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.31 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423477 | 0.83 | ATM (0.48) | ARATMRENTRIM24TRIM33 | |
| SCHEMBL3221554 | 0.74 | GPR84 (0.58) | ARATMRENTRIM24TRIM33 | |
| SCHEMBL12657696 | 0.73 | TDP1 (0.40) | ARATMRENTRIM24TRIM33 | |
| SCHEMBL15496486 | 0.72 | CYP1A2 (0.40) | AR | |
| SCHEMBL14041128 | 0.71 | CDK2 (0.36) | ARATMRENTDO2MAPT | |
| SCHEMBL31607554 | 0.70 | TRIM24 (0.60) | ARATMRENTRIM24TRIM33 | |
| SCHEMBL2143637 | 0.70 | TRIM24 (0.60) | ARATMRENTRIM24TRIM33 | |
| SCHEMBL25667710 | 0.70 | AR (0.39) | ARTDO2TRIM24TRIM33BRPF1 | |
| SCHEMBL8052787 | 0.70 | ATM (0.38) | ATMRENBRPF1SMN1; SMN2 | |
| SCHEMBL172260 | 0.69 | CYP1A2 (0.38) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039858-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |