Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496486 | 0.97 | CYP1A2 (0.40) | CYP1A2ACHEHPGDALDH1A1TSHR | |
| SCHEMBL13039532 | 0.82 | TUBB1 (0.40) | ACHEHPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL30064 | 0.79 | ACHE (0.42) | CYP1A2ACHEHPGDALDH1A1TSHR | |
| SCHEMBL15496494 | 0.78 | ERN1 (0.31) | ACHE | |
| SCHEMBL23557604 | 0.76 | IMPDH2 (0.40) | CYP1A2ALDH1A1ARCYP3A4KDM4E | |
| SCHEMBL23665424 | 0.75 | — | — | |
| SCHEMBL23665586 | 0.75 | ESR1 (0.33) | — | |
| SCHEMBL15061919 | 0.73 | NOS2 (0.45) | CCR1CCR5CCR8KDM4E | |
| SCHEMBL15724649 | 0.73 | CYP1A2 (0.43) | CYP1A2HPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL15496487 | 0.73 | ACHE (0.31) | ACHEHPGDALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133363-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-11873438-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-01-16 | — | — | US | disclosed |
| US-11873438-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-01-16 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11802243-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-31 | — | — | US | disclosed |
| US-11802243-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-31 | — | — | US | disclosed |
| US-11781069-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-20230313043-A1 | OPTICAL COMPONENT | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-2199362-A2 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2010057575-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2010-05-27 | — | — | WO | disclosed |
| US-20100108945-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-06 | — | — | US | disclosed |
| US-20100108945-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-2182046-A1 | Liquid-crystalline medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| WO-2009129911-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH, (DE) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009115186-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2009-09-24 | — | — | WO | disclosed |
| WO-2008009417-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | CYP1A2 2458/4885ACHE 1877/4885HPGD 4831/4885 |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | VIM, CDH1, LEF1 | CYP1A2 3108/4885ACHE 1365/4885HPGD 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.