Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677440 | 0.93 | MAOA (0.55) | TRPA1MAOAHTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL19682101 | 0.91 | TRPA1 (0.67) | TRPA1MAOATRPV1S1PR2S1PR4 | |
| SCHEMBL11120194 | 0.87 | TRPA1 (0.59) | TRPA1MAOATRPV1HTR2AS1PR2 | |
| SCHEMBL6680790 | 0.85 | HTR2A (0.54) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL5833581 | 0.82 | TRPA1 (0.56) | TRPA1MAOATRPV1HTR2ASMN1; SMN2 | |
| SCHEMBL1678684 | 0.82 | TRPA1 (0.58) | TRPA1TRPV1S1PR2S1PR4S1PR1 | |
| SCHEMBL6671960 | 0.82 | TRPA1 (0.58) | TRPA1TRPV1HTR2ASIGMAR1 | |
| SCHEMBL27177813 | 0.81 | TRPA1 (0.61) | TRPA1MAOATRPV1S1PR2S1PR4 | |
| SCHEMBL27370822 | 0.81 | TRPA1 (0.61) | TRPA1MAOATRPV1S1PR2S1PR4 | |
| SCHEMBL15149575 | 0.81 | TRPA1 (0.56) | TRPA1TRPV1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056602-C | Esters and amides as PLA2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-20 | — | — | CN | disclosed |
| CN-1197450-A | Esters and amides as phospholipase A2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-28 | — | — | CN | disclosed |