Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13923299 | 0.82 | MC4R (0.52) | MC4RLMNACHKAKDM4EMAPT | |
| SCHEMBL27360064 | 0.79 | KDM4E (0.38) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL20160541 | 0.78 | TNKS (0.45) | MC4RLMNACHKAALDH1A1KDM4E | |
| SCHEMBL21551702 | 0.77 | KDM4E (0.45) | MC4RLMNACHKAALDH1A1KDM4E | |
| SCHEMBL14980280 | 0.74 | KDM4E (0.46) | MC4RLMNACHKAKDM4ETDP1 | |
| SCHEMBL28319481 | 0.72 | MC4R (0.55) | MC4RLMNACHKAALDH1A1KDM4E | |
| SCHEMBL20322780 | 0.72 | HDAC6 (0.43) | MC4RLMNACHKAALDH1A1KDM4E | |
| SCHEMBL30975211 | 0.72 | NR1H2 (0.44) | MC4RLMNACHKAALDH1A1KDM4E | |
| SCHEMBL18390913 | 0.71 | GAA (0.47) | MC4RLMNACHKAALDH1A1KDM4E | |
| SCHEMBL30216078 | 0.69 | MC4R (0.40) | MC4RLMNACHKAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028364-A1 | ARYL-TRIAZOLYL AND RELATED GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2024-02-08 | — | — | WO | disclosed |