Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146456 | 0.81 | CYP2C9 (0.45) | KDM4E | |
| SCHEMBL1252213 | 0.75 | GAA (0.48) | NR1H2LMNADRD4DRD3MC4R | |
| SCHEMBL30975206 | 0.74 | METAP2 (0.50) | NR1H2LMNADRD4DRD3MC4R | |
| SCHEMBL30975198 | 0.74 | METAP2 (0.50) | NR1H2LMNADRD4DRD3MC4R | |
| SCHEMBL28319481 | 0.72 | MC4R (0.55) | LMNADRD4DRD3MC4RALDH1A1 | |
| SCHEMBL27360423 | 0.72 | MC4R (0.46) | LMNADRD4DRD3MC4RALDH1A1 | |
| SCHEMBL20332426 | 0.69 | LMNA (0.58) | LMNAMC4RALDH1A1KDM4EPTPN1 | |
| SCHEMBL12877696 | 0.69 | — | — | |
| SCHEMBL22230354 | 0.69 | LMNA (0.45) | NR1H2LMNADRD4DRD3MAP4K4 | |
| SCHEMBL20214361 | 0.69 | NR1H2 (0.63) | NR1H2ALDH1A1KDM4EPOLBRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134514-A1 | NOVEL COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | disclosed |