Urea

Urea

SCHEMBL27360704

NC(N)=O.Nc1cnc2ccccc2n1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
ALOX15 P16050 1/20 0.53
KDM4E B2RXH2 5/20 0.47
HSP90AA1 P07900 2/20 0.47
HSP90AB1 P08238 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
NPC1 O15118 2/20 0.45
MAPT P10636 2/20 0.45
RAB9A P51151 2/20 0.45
GAA P10253 3/20 0.45
PDE10A Q9Y233 1/20 0.44
PTK2 Q05397 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL28284029 0.94 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10ALOX15KDM4E
Bicarbonate SCHEMBL28314157 0.92 ALDH1A1 (0.58) ALDH1A1HPGDHSD17B10ALOX15KDM4E
Bicarbonate SCHEMBL28191578 0.90 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10ALOX15KDM4E
Bicarbonate SCHEMBL28191576 0.90 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10ALOX15KDM4E
SCHEMBL462847 0.89 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10ALOX15KDM4E
SCHEMBL27999697 0.89 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10ALOX15KDM4E
SCHEMBL29447182 0.89 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10ALOX15KDM4E
Ammonia Solution, Strong SCHEMBL22288229 0.87 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10ALOX15KDM4E
Bromide SCHEMBL7244276 0.87 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10ALOX15KDM4E
Ammonia Solution, Strong SCHEMBL27825755 0.87 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110268115-A Method of sterilization in pulp production process 栗田工业株式会社 2019-09-20 CN claimed
CN-105829289-B The integration production of urea and melamine 斯塔米卡邦有限公司 2019-07-26 CN claimed
CN-106748570-A A kind of production technology of stability urea 锦西天然气化工有限责任公司 2017-05-31 CN claimed
CN-110268115-A Method of sterilization in pulp production process 栗田工业株式会社 2019-09-20 CN disclosed
CN-106458586-B The method of quantitative ammonium hydrogen carbonate in aminoquinoxaline solid sample AY实验室有限公司 2019-09-10 CN disclosed
CN-209081009-U A kind of small particle urea cooling conveying device 灵谷化工有限公司 2019-07-09 CN disclosed
CN-106748570-A A kind of production technology of stability urea 锦西天然气化工有限责任公司 2017-05-31 CN disclosed
CN-106588183-A Production process of boron-nitrogen fertilizer 锦西天然气化工有限责任公司 2017-04-26 CN disclosed
CN-103748071-B urea finishing method 斯塔米卡邦有限公司 2017-03-08 CN disclosed
CN-106403651-A Tube bundle equipment with liquid flow regulator elements 塞彭公司 2017-02-15 CN disclosed
CN-1061645-C Process for producing urea RES AND DESIGN INST OF CARBUMI (RU) 2001-02-07 CN disclosed
CN-1188108-A Process for producing urea RES AND DESIGN INST OF CARBAMI (RU) 1998-07-22 CN disclosed