SCHEMBL462847

SCHEMBL462847

Nc1cnc2ccccc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 4/20 0.52
HPGD P15428 4/20 0.52
MAPT P10636 4/20 0.52
HSD17B10 Q99714 3/20 0.52
GAA P10253 3/20 0.52
PDE10A Q9Y233 1/20 0.52
NCF1 P14598 1/20 0.50
NOS2 P35228 1/20 0.50
BACE1 P56817 1/20 0.50
NPC1 O15118 4/20 0.48
RAB9A P51151 3/20 0.48
PDPK1 O15530 2/20 0.48
GPR3 P46089 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
CASP1 P29466 1/20 0.47
MAPK10 P53779 1/20 0.47
CASP7 P55210 1/20 0.47
ALOX15 P16050 1/20 0.47
POLB P06746 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27999697 1.00 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDMAPTHSD17B10
SCHEMBL29447182 1.00 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDMAPTHSD17B10
Hydrochloric Acid SCHEMBL27776055 0.98 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPTHSD17B10
Ammonia Solution, Strong SCHEMBL22288229 0.98 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPTHSD17B10
Bromide SCHEMBL7244276 0.98 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPTHSD17B10
Ammonia Solution, Strong SCHEMBL27825755 0.98 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPTHSD17B10
Benzene SCHEMBL28261497 0.98 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPTHSD17B10
Bromide SCHEMBL27818577 0.95 PDE10A (0.48) ALDH1A1KDM4EHPGDMAPTHSD17B10
Carbon Dioxide SCHEMBL28214588 0.91 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDMAPTHSD17B10
Urea SCHEMBL27360704 0.89 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2556 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3676261-B1 SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTANE AND 2-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS CHRONOS THERAPEUTICS LTD (GB) 2024-12-18 EP claimed
CN-118994040-A Method for preparing 3-aminoquinoxaline-2 (1H) -ketone compound by photocatalysis 南京工业大学 2024-11-22 CN claimed
CN-118453604-A Application of aminoquinoxaline derivative in preparation of antitumor pharmaceutical composition 广西科技大学 2024-08-09 CN claimed
CN-118125986-A Quinoxaline oxynitride and preparation method thereof 中国科学院大连化学物理研究所 2024-06-04 CN claimed
CN-118005569-A 6-Aminoquinoxaline compound and preparation method and application thereof 华南理工大学 2024-05-10 CN claimed
EP-2440546-B1 COMPOUNDS USEFUL FOR TREATING PREMATURE AGING AND IN PARTICULAR PROGERIA ABIVAX (FR) 2022-12-28 EP claimed
US-20220331299-A1 SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTANE AND 2-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS CHRONOS THERAPEUTICS LIMITED (GB) 2022-10-20 US claimed
CN-112538053-B Method for synthesizing nitroquinoxaline or derivative thereof and aminoquinoxaline or derivative thereof 同济大学 2022-09-02 CN claimed
CN-110867603-B Polypyrrole-quinoxaline-negative-electrode-based all-water-system mixed flow battery and preparation method thereof 常州大学 2022-03-22 CN claimed
EP-3359538-B9 1,4,8-TRIAZAPHENANTHRENE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS INST DU CERVEAU ET DE LA MOELLE EPINIERE (FR) 2021-06-16 EP claimed
CN-1132655-A Process for producing high-porosity non-evaporable getter materials and materials thus obtained GETTERS SPA (IT) 1996-10-09 CN claimed
CN-1118712-A Multi-step process for reucing no and so NALCO FUEL TECH (US) 1996-03-20 CN claimed
CN-1114593-A Process for reducing NOx, SOx, chlorine and particulates while maintaining reliable operation of an electrostatic precipitator NALCO FUEL TECH (US) 1996-01-10 CN claimed
CN-1113826-A Process for improving the performance of an electrostatic precipitator NALCO FUEL TECH (US) 1995-12-27 CN claimed
CN-1028346-C Production method of calcium phosphide pesticide WU YANJIE (CN) 1995-05-10 CN claimed
CN-1082668-A Improved high-capacity getter pump GETTERS SPA (IT) 1994-02-23 CN claimed
CN-1082669-A Improved high-capacity getter pump GETTERS SPA (IT) 1994-02-23 CN claimed
CN-1071510-A NOx sensor and detection method CATALYTICA INC (US) 1993-04-28 CN claimed
CN-1058133-A A kind of producing method for calcium phosphide pesticide WU YANJIE (CN) 1992-01-29 CN claimed
CN-88100644-A The hydrolysis of delayed metal phosphoride 1988-11-02 CN claimed