Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362659 | 0.83 | CYP1A2 (0.39) | HPGDALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL12890296 | 0.82 | ALDH1A1 (0.43) | HPGDALDH1A1PSMB11PSMA7PSMB1 | |
| SCHEMBL21576120 | 0.76 | LMNA (0.39) | ALDH1A1MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL1532612 | 0.74 | HDAC3 (0.41) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL27942339 | 0.73 | HDAC3 (0.42) | ALDH1A1GAAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7004600 | 0.73 | CCNC (0.42) | ALDH1A1MAPTKDM4ELMNAHTT | |
| SCHEMBL13593756 | 0.73 | KDM4E (0.59) | HPGDALDH1A1PSMB11PSMA7PSMB1 | |
| SCHEMBL3420004 | 0.73 | ALDH1A1 (0.61) | ALDH1A1GAAPSMB11PSMA7PSMB1 | |
| SCHEMBL19116553 | 0.73 | HPGD (0.45) | HPGDALDH1A1PSMB11PSMA7PSMB1 | |
| SCHEMBL1648472 | 0.72 | KDM4E (0.45) | KDM4EHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050433-A1 | ALLOSTERIC MODULATORS OF ANDROGEN RECEPTOR COACTIVATOR RECRUITMENT FOR CRPC THERAPY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-03-07 | — | — | WO | disclosed |