Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822408 | 0.83 | KDM4E (0.60) | KDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL27507950 | 0.80 | NPC1 (0.56) | KDM4EMAPTALDH1A1NPC1CNR2 | |
| SCHEMBL23045524 | 0.80 | KDM4E (0.46) | KDM4EMAPTALDH1A1 | |
| SCHEMBL28763406 | 0.78 | KDM4E (0.63) | KDM4EMAPTALDH1A1CNR2CNR1 | |
| SCHEMBL25437053 | 0.78 | NPC1 (0.56) | KDM4EALDH1A1NPC1CNR2CNR1 | |
| SCHEMBL27361848 | 0.78 | EDNRB (0.54) | KDM4EMAPTALDH1A1MAPK1 | |
| SCHEMBL6017853 | 0.77 | SMN1; SMN2 (0.53) | KDM4EMAPTALDH1A1NPC1NPSR1 | |
| Biphenyl SCHEMBL28481359 | 0.76 | KDM4E (0.63) | KDM4EMAPTALDH1A1CNR2PSEN1 | |
| Benzene SCHEMBL28478449 | 0.74 | CNR2 (0.62) | KDM4EMAPTCNR2PSEN1PSEN2 | |
| SCHEMBL10762568 | 0.73 | CCR2 (0.55) | KDM4EPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067886-A | New urea derivatives, their preparation method and pharmaceutical composition thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-01-13 | — | — | CN | disclosed |