Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.54 |
| ▸ | EDNRA | P25101 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23045524 | 0.85 | KDM4E (0.46) | EDNRBEDNRAMAPK8HDAC6HDAC1 | |
| SCHEMBL7744033 | 0.81 | F10 (0.56) | EDNRBEDNRACYP19A1FOLH1P2RX4 | |
| SCHEMBL29015820 | 0.78 | FOLH1 (0.49) | CYP19A1FOLH1P2RX4KDM4EMEN1 | |
| SCHEMBL5419800 | 0.78 | SERPINE1 (0.66) | EDNRBEDNRAFOLH1MAPK8SERPINE1 | |
| SCHEMBL27361847 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL8856902 | 0.77 | EDNRB (0.58) | EDNRBEDNRAFOLH1MAPK8SERPINE1 | |
| SCHEMBL19133588 | 0.77 | EDNRB (0.59) | EDNRBEDNRACYP19A1FOLH1SERPINE1 | |
| SCHEMBL6017853 | 0.76 | SMN1; SMN2 (0.53) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5415705 | 0.76 | MAPK8 (0.52) | MAPK8HDAC6HDAC1KDM4EMEN1 | |
| SCHEMBL5424000 | 0.76 | SERPINE1 (0.62) | EDNRBEDNRAFOLH1MAPK8SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067886-A | New urea derivatives, their preparation method and pharmaceutical composition thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-01-13 | — | — | CN | disclosed |