Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773822 | 0.93 | GPR119 (0.52) | PIK3CDGPR119 | |
| SCHEMBL5673329 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7900769 | 0.80 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL4102372 | 0.80 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL26775838 | 0.80 | PIK3CD (0.49) | PIK3CD | |
| SCHEMBL4003618 | 0.78 | GPR119 (0.49) | PIK3CDGPR119 | |
| SCHEMBL23702818 | 0.77 | PIK3CD (0.47) | PIK3CD | |
| SCHEMBL23708849 | 0.77 | PIK3CD (0.47) | PIK3CD | |
| SCHEMBL17664543 | 0.77 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL17664530 | 0.77 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039858-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |