Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362161 | 0.84 | SIRT1 (0.50) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL231042 | 0.78 | SIRT1 (0.71) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL1447741 | 0.77 | KDM4E (0.59) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL6934354 | 0.77 | SIRT1 (0.53) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL11013368 | 0.76 | SIRT1 (0.51) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL232529 | 0.76 | MEN1 (0.53) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL8534213 | 0.76 | SIRT1 (0.56) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL8530243 | 0.76 | MEN1 (0.53) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL27362928 | 0.76 | SIRT1 (0.56) | SIRT1POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL26676266 | 0.76 | SIRT1 (0.51) | SIRT1POLBKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035268-A2 | TAU PATHWAY MODULATORS | QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT (QA) | 2024-02-15 | — | — | WO | disclosed |