Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362055 | 0.84 | SIRT1 (0.46) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL231042 | 0.81 | SIRT1 (0.71) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL2024004 | 0.78 | ALDH1A1 (0.59) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL6935437 | 0.78 | SIRT1 (0.58) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL27362103 | 0.78 | POLB (0.52) | SIRT1POLBCA12CA1CA2 | |
| SCHEMBL8228023 | 0.77 | SIRT1 (0.56) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL10482126 | 0.77 | SIRT1 (0.56) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL8531499 | 0.77 | SIRT1 (0.56) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL6781026 | 0.77 | NPC1 (0.56) | SIRT1POLBNSD2CA12CA1 | |
| SCHEMBL1775501 | 0.77 | POLB (0.56) | SIRT1POLBNSD2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035268-A2 | TAU PATHWAY MODULATORS | QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT (QA) | 2024-02-15 | — | — | WO | disclosed |