SCHEMBL27362519

SCHEMBL27362519

CC(C)[C@]12CCCCC1CC[C@H]1[C@@H]3CCC[C@@]3(C)CC[C@@H]12

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CDK5 Q00535 1/20 0.48
CDK5R1 Q15078 1/20 0.48
NR1I3 Q14994 1/20 0.48
MBOAT4 Q96T53 3/20 0.42
GRIN1 Q05586 8/20 0.41
GRIN2B Q13224 8/20 0.41
CYP19A1 P11511 4/20 0.36
AKR1B10 O60218 1/20 0.34
AKR1B1 P15121 1/20 0.34
EFNA1 P20827 1/20 0.34
EPHA2 P29317 1/20 0.34
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
GPBAR1 Q8TDU6 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4998837 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL157802 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL30331615 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL10343473 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL474980 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL24451237 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL317924 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL157803 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL4998832 0.78 CDK5 (0.64) CDK5CDK5R1NR1I3MBOAT4GRIN1
SCHEMBL11241858 0.77 CDK5 (0.62) CDK5CDK5R1NR1I3MBOAT4GRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1069734-A 11.19-the synthetic method of cyclopolymerized pregnenone analogue SHANGHAI INST OF FAMILY PLANNI (CN) 1993-03-10 CN disclosed