Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.62 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516103 | 0.84 | NNMT (0.64) | NNMTMKNK1MKNK2SMN1; SMN2PTPN1 | |
| SCHEMBL1882423 | 0.83 | NNMT (0.67) | NNMTMKNK1MKNK2SMN1; SMN2PTPN1 | |
| SCHEMBL12019310 | 0.83 | NNMT (0.67) | NNMTMKNK1MKNK2SMN1; SMN2MAOA | |
| SCHEMBL20812214 | 0.81 | NNMT (0.60) | NNMTMKNK1MKNK2GABRA1 | |
| SCHEMBL65277 | 0.80 | NNMT (0.68) | NNMTMKNK1MKNK2SMN1; SMN2PTPN1 | |
| SCHEMBL13701799 | 0.80 | NNMT (0.58) | NNMTMKNK1MKNK2SMN1; SMN2PTPN1 | |
| SCHEMBL18228074 | 0.80 | NNMT (0.72) | NNMTMKNK1MKNK2SMN1; SMN2MAOA | |
| SCHEMBL105066 | 0.78 | NNMT (0.70) | NNMTMKNK1MKNK2SMN1; SMN2MAOA | |
| SCHEMBL29757598 | 0.78 | NNMT (0.70) | NNMTMKNK1MKNK2KDM4EMAPT | |
| SCHEMBL29514668 | 0.78 | NNMT (0.70) | NNMTMKNK1MKNK2SMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050433-A1 | ALLOSTERIC MODULATORS OF ANDROGEN RECEPTOR COACTIVATOR RECRUITMENT FOR CRPC THERAPY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-03-07 | — | — | WO | disclosed |