Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.58 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 2/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701697 | 0.84 | MAPT (0.62) | HPGDSGABRA5MAPTLMNAHTT | |
| SCHEMBL14516103 | 0.81 | NNMT (0.64) | NNMTHPGDSGABRA5MKNK1MKNK2 | |
| SCHEMBL13701718 | 0.81 | GRN (0.63) | HPGDSGABRA5GRNSORT1RAB9A | |
| SCHEMBL6932337 | 0.81 | GABRA5 (0.51) | HPGDSGABRA5SMN1; SMN2MEN1MAPT | |
| SCHEMBL13701755 | 0.81 | L3MBTL1 (0.65) | GABRA5MAPT | |
| SCHEMBL12019310 | 0.80 | NNMT (0.67) | NNMTMKNK1MKNK2SMN1; SMN2PTPN1 | |
| SCHEMBL1882423 | 0.80 | NNMT (0.67) | NNMTMKNK1MKNK2SMN1; SMN2PTPN1 | |
| SCHEMBL958814 | 0.80 | HDAC1 (0.46) | HPGDSGABRA5MAPTLMNAHTT | |
| SCHEMBL27362572 | 0.80 | NNMT (0.62) | NNMTMKNK1MKNK2SMN1; SMN2PTPN1 | |
| SCHEMBL13701640 | 0.80 | MEN1 (0.60) | HPGDSMKNK1MKNK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150972-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-05-18 | — | — | US | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | NNMT 1226/4885HPGDS 18/4885GABRA5 3805/4885 |
| US-20230150972-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | SCN1B, SCN1A, SCN2B | NNMT 1584/4885HPGDS 4131/4885GABRA5 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.