Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153415 | 0.88 | STS (0.66) | STSMAOBXDHMAOANPC1 | |
| SCHEMBL18153371 | 0.83 | STS (0.59) | STSMAOBXDHMAOANPC1 | |
| SCHEMBL14879967 | 0.82 | XDH (0.74) | STSMAOBXDHMAOANPC1 | |
| SCHEMBL20127033 | 0.79 | STS (0.54) | STSMAOBXDHMAOANPC1 | |
| SCHEMBL27085607 | 0.77 | XDH (0.82) | STSMAOBXDHMAOANPC1 | |
| SCHEMBL18153397 | 0.75 | ESR2 (0.74) | STSMAOBMAOANPC1RAB9A | |
| SCHEMBL31695377 | 0.75 | ESR2 (0.74) | STSMAOBMAOANPC1RAB9A | |
| SCHEMBL7886515 | 0.75 | CA12 (0.50) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL18535597 | 0.75 | MAOB (0.62) | STSMAOBMAOANPC1RAB9A | |
| SCHEMBL519168 | 0.74 | DRD2 (0.58) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10718028-B2 | Fluorescent probes for abasic site detection | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-07-21 | — | — | US | disclosed |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| WO-2016168467-A2 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY (US) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10718028-B2 | Fluorescent probes for abasic site detection | OGG1, UNG, AP2B1 | STS 3008/4885MAOB 1711/4885XDH 216/4885 |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | OGG1, UNG, AP2B1 | STS 3008/4885MAOB 1711/4885XDH 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.