Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GALR2 | O43603 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | USP10 | Q14694 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15808259 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL940019 | 0.81 | PRKCZ (0.45) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL2930841 | 0.79 | CACNA1C (0.48) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL5467919 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL27750330 | 0.76 | TSHR (0.49) | ALDH1A1SMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL4728649 | 0.75 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL2932351 | 0.75 | POLB (0.51) | ALDH1A1SMN1; SMN2POLBKMT2AGAA | |
| SCHEMBL11525725 | 0.75 | GAA (0.45) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL3369777 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL24558172 | 0.74 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060841-A | Quinazoline derivant and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-05-06 | — | — | CN | disclosed |