Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385630 | 0.85 | TDP1 (0.36) | TDP1 | |
| SCHEMBL6700157 | 0.84 | TDP1 (0.40) | TDP1GNAO1GNAI3GNAI1PRKCD | |
| SCHEMBL10385678 | 0.82 | TDP1 (0.39) | TDP1 | |
| SCHEMBL26626969 | 0.82 | TDP1 (0.38) | TDP1 | |
| SCHEMBL10385183 | 0.81 | TDP1 (0.41) | TDP1 | |
| SCHEMBL28068690 | 0.77 | GBA1 (0.41) | GNAO1GNAI3GNAI1GBA1GBA2 | |
| SCHEMBL10385681 | 0.77 | TDP1 (0.35) | TDP1 | |
| SCHEMBL10386722 | 0.76 | TDP1 (0.38) | TDP1 | |
| SCHEMBL1139996 | 0.76 | TDP1 (0.36) | TDP1 | |
| SCHEMBL27827297 | 0.76 | GBA1 (0.43) | GNAO1GNAI3GNAI1GBA1GBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052144-A | The Compounds and methods for of diagnosis and treatment cancer | AUSTRALIAN COMMERCIAL RESEARCH (AU) | 1991-06-12 | — | — | CN | disclosed |