Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363044 | 0.84 | TDP1 (0.40) | TDP1GNAO1GNAI3GNAI1TAAR1 | |
| SCHEMBL506128 | 0.82 | TDP1 (0.42) | TDP1 | |
| SCHEMBL10385673 | 0.81 | TDP1 (0.39) | TDP1 | |
| SCHEMBL5474455 | 0.77 | TDP1 (0.34) | TDP1 | |
| SCHEMBL3260061 | 0.77 | GNAO1 (0.40) | GNAO1GNAI3GNAI1TAAR1GBA1 | |
| SCHEMBL3103755 | 0.75 | GNAO1 (0.40) | GNAO1GNAI3GNAI1TAAR1GBA1 | |
| SCHEMBL27282980 | 0.75 | TDP1 (0.47) | TDP1TAAR1 | |
| SCHEMBL28166797 | 0.74 | GNAO1 (0.37) | GNAO1GNAI3GNAI1TAAR1GBA1 | |
| SCHEMBL23921639 | 0.73 | GNAO1 (0.42) | GNAO1GNAI3GNAI1TAAR1GBA1 | |
| SCHEMBL3106189 | 0.73 | TAAR1 (0.45) | GNAO1GNAI3GNAI1TAAR1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004244376-A | METHOD FOR PRODUCING AMINOETHYLARYLPIPERAZINE DERIVATIVE | NISSAN CHEM IND LTD | 2004-09-02 | — | — | JP | disclosed |
| EP-0173634-B1 | 4-(ARYLPIPERAZINYLETHYLAMINOETHOXY) PHENOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL APPLICATION | CORTIAL S.A. (FR) | 1988-08-31 | — | — | EP | disclosed |
| EP-0173634-A1 | 4-(Arylpiperazinylethylaminoethoxy) phenol derivatives, process for their preparation and their therapeutical application | CORTIAL S.A. (FR) | 1986-03-05 | — | — | EP | disclosed |