SCHEMBL1139996

SCHEMBL1139996

CC(O)C1CNCCN1CCS(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10385678 0.80 TDP1 (0.39) TDP1
SCHEMBL10385183 0.78 TDP1 (0.41) TDP1
SCHEMBL9567014 0.76 LMNA (0.31)
SCHEMBL2475309 0.76
SCHEMBL26626969 0.76 TDP1 (0.38) TDP1
SCHEMBL1701174 0.76 TAAR1 (0.34) TDP1
SCHEMBL27363044 0.76 TDP1 (0.40) TDP1
SCHEMBL10385681 0.74 TDP1 (0.35) TDP1
SCHEMBL62392 0.74 CA1 (0.35) TDP1
SCHEMBL2057256 0.73 TDP1 (0.36) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111763709-A Preparation method of coliform group detection reagent by enzyme substrate method 浙江泰林生命科学有限公司 2020-10-13 CN claimed
CN-111763709-A Preparation method of coliform group detection reagent by enzyme substrate method 浙江泰林生命科学有限公司 2020-10-13 CN disclosed
EP-1149899-B9 Culture medium for avian totipotential embryonic cells AGRONOMIQUE INST NAT RECH (FR) 2011-09-21 EP disclosed
EP-1149899-B1 Culture medium for avian totipotential embryonic cells AGRONOMIQUE INST NAT RECH (FR) 2011-02-23 EP disclosed
EP-1148122-B1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR KYOWA HAKKO BIO CO LTD (JP) 2009-09-02 EP disclosed
US-20090148916-A1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-06-11 US disclosed
US-7470528-B2 DNA encoding hydroxylase KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-12-30 US disclosed
US-20080261273-A1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITORS KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-10-23 US disclosed
EP-1146126-B1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITORS KYOWA HAKKO KOGYO KK (JP) 2007-04-25 EP disclosed
US-20060154348-A1 Process for producing HMG-CoA reductase inhibitors KYOWA HAKKO KOGYO CO. LTD (JP) 2006-07-13 US disclosed
EP-1148122-A1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-10-24 EP disclosed
EP-1146126-A1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITORS KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-10-17 EP disclosed
US-6300329-B1 HETEROCYCLIC PYRIDO(1,2-A)PYRAZINE COMPOUNDS FOR TREATMENT OF PARKINSON'S DISEASE PFIZER PRODUCTS INC. 2001-10-09 US disclosed
EP-1115402-A1 PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PARKINSON'S DISEASE, ADHD AND MICROADENOMAS Pfizer Products Inc. (US) 2001-07-18 EP disclosed
EP-1003739-A2 2-(4-ARYL OR HETEROARYL-PIPERAZIN-1-YLMETHYL)-1H-INDOLE DERIVATIVES Pfizer Products Inc. (US) 2000-05-31 EP disclosed
WO-2000016777-A1 PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PARKINSON'S DISEASE, ADHD AND MICROADENOMAS PFIZER PRODUCTS INC. (US) 2000-03-30 WO disclosed
EP-0953567-A2 Bicyclic substituted piperazine-, piperidine- and tetrahydropyridine derivatives, their preparation and their use as agents with central dopaminergic (dopamine D4 receptor) activity Pfizer Products Inc. (US) 1999-11-03 EP disclosed
WO-1999009025-A2 2-(4-ARYL OR HETEROARYL-PIPERAZIN-1-YLMETHYL)-1H-INDOLE DERIVATIVES INTERACTING WITH THE DOPAMINE D4 RECEPTOR PFIZER PRODUCTS INC. (US) 1999-02-25 WO disclosed
EP-0787180-A1 ACTIVE RETINOIC ACID FREE CULTURE MEDIUM FOR AVIAN TOTIPOTENTIAL EMBRYONIC CELLS INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA) (FR) 1997-08-06 EP disclosed
WO-1996012793-A1 ACTIVE RETINOIC ACID FREE CULTURE MEDIUM FOR AVIAN TOTIPOTENTIAL EMBRYONIC CELLS INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 1996-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090148916-A1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR COASY, HMGCR, BLVRB TDP1 1620/4885
US-20060154348-A1 Process for producing HMG-CoA reductase inhibitors COASY, HMGCR, BLVRB TDP1 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.