Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905179 | 0.91 | SMN1; SMN2 (0.44) | TP53SMN1; SMN2ALDH1A1GLATSHR | |
| SCHEMBL7912917 | 0.83 | NPSR1 (0.40) | TP53SMN1; SMN2ALDH1A1GLATSHR | |
| SCHEMBL27831653 | 0.83 | CYP3A4 (0.39) | TP53ALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL28571248 | 0.81 | TP53 (0.49) | TP53SMN1; SMN2ALDH1A1GLATSHR | |
| SCHEMBL27599059 | 0.79 | CYP3A4 (0.46) | TP53SMN1; SMN2ALDH1A1GLATSHR | |
| SCHEMBL7915786 | 0.77 | NPSR1 (0.44) | TP53SMN1; SMN2ALDH1A1GLATSHR | |
| SCHEMBL6131273 | 0.74 | TP53 (0.62) | TP53SMN1; SMN2ALDH1A1GLATSHR | |
| SCHEMBL20503326 | 0.74 | NPC1 (0.47) | TP53SMN1; SMN2ALDH1A1TSHRCES2 | |
| SCHEMBL7918978 | 0.72 | ALDH1A1 (0.41) | TP53ALDH1A1TSHRHPGDL3MBTL1 | |
| SCHEMBL11361015 | 0.72 | NPSR1 (0.40) | TP53SMN1; SMN2ALDH1A1GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051354-A | Replace cycloalkanes also [b] indoline-and-indol-7 sulfonamide | BAYER AG (DE) | 1991-05-15 | — | — | CN | disclosed |