SCHEMBL7918978

SCHEMBL7918978

NN(OC(=O)c1ccccc1C(=O)ON(N)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 5/20 0.39
ALOX15 P16050 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CTNNB1 P35222 1/20 0.39
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 2/20 0.37
ATM Q13315 1/20 0.37
CFTR P13569 1/20 0.37
POLB P06746 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915786 0.81 NPSR1 (0.44) ALDH1A1NPSR1TSHRALOX15TDP1
SCHEMBL28336709 0.76 POLB (0.44) ALDH1A1NPSR1TSHRALOX15TDP1
SCHEMBL7912917 0.76 NPSR1 (0.40) ALDH1A1NPSR1TSHRALOX15TDP1
SCHEMBL11361015 0.76 NPSR1 (0.40) ALDH1A1NPSR1TSHRTDP1L3MBTL1
SCHEMBL7905179 0.76 SMN1; SMN2 (0.44) ALDH1A1NPSR1TSHRTDP1L3MBTL1
SCHEMBL27363324 0.72 TP53 (0.50) ALDH1A1TSHRL3MBTL1TP53MAPK1
SCHEMBL9769555 0.70 NPSR1 (0.52) ALDH1A1NPSR1ALOX15TDP1L3MBTL1
SCHEMBL27903557 0.70 TSHR (0.50) ALDH1A1TSHRALOX15TDP1L3MBTL1
SCHEMBL8415953 0.68 ALOX15 (0.45) ALDH1A1NPSR1TSHRALOX15TDP1
SCHEMBL27460841 0.68 ALDH1A1 (0.56) ALDH1A1TSHRALOX15TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed